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Carbimazole works by preventing iodine from coming together with other components to form thyroid hormones.

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Although both liothyronine (T3) and T4 can be elevated in hyperthyroidism, serum T4 levels are primarily used in diagnosis.

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Two cases, ages 62 and 75 years, had onset of jaundice 3 and 5 weeks after starting antithyroid medications, with prolonged cholestasis in patient in whom methimazole was continued).

Others who have been treated successfully develop an underactive thyroid gland (hypothyroidism) in the future.

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