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I have been on Femara for almost 5 years now. My oncologist says that Femara is the reason of my improvements. My tumors naturally stopped growing since I started taking this medication. And the only side effect that I have noticed was light migraine after taking the drug, but it is almost unnoticeable. Three of my friends (whom I met at the hospital when I was just starting visiting my oncologist regularly) also started taking Femara simultaneously with me. They report improvement in this or that degree, but still they are happy with the way Femara works. Some of them had noticed hair thinning during treatment, but sometimes you just have to choose.

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As SERMs, they were able to prevent receptor mediated side effects such as gynecomastia, but they were completely ineffective at managing systemic estrogen levels.

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